S.N. Vyshelesski Institute of Experimental Veterinary offers consumers an inactivated emulsified vaccine for the prevention of colibacillosis and klebsiellosis in calves under a manufacturing agreement and is looking for partners interested in a distribution services agreement.

PURPOSE:
The vaccine is used to immunize heavily pregnant cows and heifers in cattle farms that are unfavorable and threatened by colibacillosis and klebsiosis.

DESCRIPTION:
Liquid (homogeneous emulsion) white or cream color. During storage, a transparent layer is allowed to form on the surface in the upper part of the emulsion, which disappears when shaken.

CHARACTERISTIC:
The vaccine is made from strains of Escherichia coli bacteria with adhesive antigens F41, K88 (F4), K99 (F4), A20, Klebsiella pneumoniae, inactivated by formaldehyde and emulsified in an oil adjuvant. Causes the production of specific antibodies against the causative agents of colibacillosis and klebsiellosis in immunized animals.

APPLICATION:
A homogeneous vaccine heated to a temperature of 25.0 ± 2.0 ° C is administered intramuscularly into the middle third of the neck according to the following scheme:

Animal	Vaccination time	Frequency and interval of vaccination	Dose, cubic cm.
Pregnant cows	45-30 days before calving	once	2,0
Heifers	two months before calving	twice,15 days	2.0
Calves	on days 5-10 of life	once	1.0

WAITING PERIOD:
The slaughter of animals, the use of slaughter products and milk for food purposes is permitted after the use of the vaccine without restrictions.

RELEASE FORM:
Sterile glass bottles of 10.0; 20.0; 50.0; 100.0; 200.0 or 400 cubic cm, sealed with rubber plugs and rolled metal caps.

STORAGE CONDITIONS:
The shelf life of the vaccine is 24 months from the date of manufacture, provided that it is stored and transported in a dry place protected from light at a temperature of plus 2 to plus 8 ° C. The vaccine can be transported at plus 15 °C for 10 days.

Download full instructions (in Russian). View registration certificate (in Russian).
More details on the institute's website (in Russian).

Vaccines and drugs were developed and tested by the Institute’s staff, and also tested in accredited laboratories.

The high level of development of animal husbandry in the Republic of Belarus is largely ensured by the efforts of veterinary medicine and its scientific and methodological center, which is the Republican Unitary Enterprise “S.N. Vyshelesski Institute of Experimental Veterinary".

Areas of activity of the Institute:
✔ development and improvement of methods for diagnosis, prevention, treatment, measures to combat infectious, parasitic and non-contagious diseases of farm animals, birds, bees;
✔ creation of modern vaccines, highly specific diagnostics, drugs, metabolic correction agents that provide veterinary protection of animals and obtain environmentally friendly livestock products;
✔ provision of scientific and practical assistance to the farms of the republic;
✔ training of highly qualified scientific personnel.

The tasks facing the Institute:
✔ conducting fundamental and applied research in the field of veterinary medicine in accordance with the main directions of economic and social development of the agro-industrial complex of the Republic of Belarus;
✔ conducting fundamental and applied research to study the mechanisms of immunity formation and the development of methods for its directed regulation;
✔ development of forecasts and programs for veterinary medicine;
✔ epizootological monitoring of the most common and parasitic infectious animal diseases, development of short-term and long-term forecasts of their occurrence and degree of manifestation;
✔ development of new and improvement of existing competitive means and methods for the diagnosis, prevention and treatment of infectious, parasitic and non-contagious animal diseases, the creation of integrated systems that ensure the protection of human health, the veterinary welfare of animal husbandry, obtaining environmentally friendly and high sanitary quality livestock products;
✔ isolation and study of the genetic, molecular and biological properties of pathogens of infectious diseases, selection and collection of useful strains that are promising for the creation of diagnosticums and vaccines;
✔ development of technologies for the production of veterinary drugs, vaccines, chemicals, antiparasitic agents.

Consumers interested in purchasing inactivated emulsified vaccine for the prevention of colibacillosis and klebsiellosis in calves under a manufacturing agreement.

Partners interested in purchasing inactivated emulsified vaccine for the prevention of colibacillosis and klebsiellosis in calves under a distribution services agreement.