Institute of Physiology  
220072 Minsk, Academic St., 28

A method for implementing the somatotopic principle of perineural migration of mesenchymal stem cells









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Tatiana Khrustaleva
+375 17 378 1630
The Institute of Physiology offers consumers a method (technology) for implementing the somatotopic principle of perineural migration of mesenchymal stem cells under a commercial agreement with technical assistance and is looking for partners to conclude an agreement on scientific cooperation.
The currently existing methods for restoring damaged tissues of the central nervous system are not effective enough to restore the working capacity of patients with brain injury or stroke.

The methodical method of perineural migration of mesenchymal stem cells is the basis for achieving their selective movement to areas of damage to internal organs and the central nervous system after being introduced into the receptive fields of cranial, somatic and autonomic nerves, which is accompanied by activation of trophic processes and acceleration of the restoration of the activity of functional systems impaired as a result injury.
Advantages and Innovations
The developed method provides targeted migration of mesenchymal stem cells to the damaged area of the brain, which is accompanied by the activation of reparative processes in the defective tissue area and faster and more effective restoration of functions.

The development has a social orientation and is focused on the effective restoration of the working capacity of patients with strokes.
Stage of development
Field tested/evaluated (TRL8)
Funding source
State budged
IPR status
Exclusive rights
Secret know-how
Sector group

Organization information

R&D institution
Year established
NACE keywords
Q.86.90 - Other human health activities
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
M.74.90 - Other professional, scientific and technical activities n.e.c.
Turnover (in EUR)
Already engaged in transnational cooperation
Additional comments
The Institute is a leading scientific institution coordinating physiological research in the Republic of Belarus. The institute successfully carries out fundamental and applied research aimed at developing methods for the prevention and correction of pathological conditions of hypoxic, ischemic and inflammatory origin, and develops new devices and methods for their therapeutic and prophylactic use. The main scientific activity of the divisions is currently focused on studying the mechanisms of the formation of pathological conditions of the body (primarily hypoxic and neurodestructive) and substantiating new technologies for prevention, treatment and rehabilitation. Particular attention is paid to the development of complex methods for the treatment of malignant tumors using effectors of the blockade of metabolism and high-intensity pulsed magnetic fields and methods for controlling the proliferation of tumor cells based on changes in the functional state of neuroreceptors in vitro and in vivo, as well as the development of a method for immunotherapy of patients suffering from pancreatic cancer. , using autologous dendritic cells primed with tumor antigens and elucidating new mechanisms of tumor formation, substantiation of prevention methods. Research is underway on the molecular mechanisms of proliferation, differentiation, and oncogenesis; physiological and therapeutic effect of physical factors and the development of new technologies of physiotherapy and physiotherapy equipment and experimental analysis of the positive and negative aspects of the use of nanoparticles and heterocyclic compounds in biomedical technologies. The neurophysiological bases of dysregulation of the functions of internal organs during ischemia of the nervous tissue of various origins are being studied. Works on the physiology of nutrition and sports are being carried out. Preclinical studies of drugs and nanomaterials are underway.
Languages spoken

Information about partnership

Type of partnership considered
Commercial agreement with technical assistance
Research cooperation agreement
Type and role of partner sought
Consumers interested in purchasing the technology for the implementation of the somatotopic principle of perineural migration of mesenchymal stem cells under a commercial agreement with technical assistance.

Partners interested in concluding an research cooperation agreement.
Type and size of partner sought
SME 51-250
SME 11-50
SME <= 10
R&D Institution
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Statistics since 12.03.2022 10:52:02