Institute of Physiology

http://physiology.by/  
220072 Minsk, Academic St., 28

Mechanisms of positive and negative impact on the functional status of the body of food products, diets and biologically active food supplements and the functional role of normal intestinal microflora

COUNTRY OF ORIGIN

IDENTIFIER

BO7476

PUBLISHED

2023-08-24

LAST UPDATE

2023-08-29

DEADLINE

Linked profile in other language
Responsible
Tatiana Khrustaleva
+375 17 378 1630
biblio@fizio.bas-net.by
Summary
The Institute of Physiology offers consumers services to study the mechanisms of positive and negative effects on the functional status of the body of foods, diets and biologically active food supplements and the functional role of the normal intestinal microflora and its changes depending on the diet or the effects of biologically active substances under an outsourcing agreement or a subcontracting and is looking for partners to conclude a research cooperation agreement.
Description
Services are offered for:
- experimental study of the mechanisms of positive and negative impact on the functional status of the body of food products, diets and biologically active food supplements;
- study of the functional role of the normal intestinal microflora and its changes depending on the diet or the effects of biologically active substances;
- The study of the "gut-brain" axis in the norm and in the pathogenesis of neurological diseases.

The laboratory is equipped with equipment for analyzing behavioral responses, assessing seizure activity in laboratory animals, conducting electrophysiological and biochemical studies, etc.
Advantages and Innovations
Unique research methods. Highly qualified staff.
Stage of development
Already on the market
Funding source
State budged
Internal
IPR status
Exclusive rights
Secret know-how
Sector group
BioChemTech
Healthcare

Organization information

Type
R&D institution
Year established
1953
NACE keywords
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
M.74.90 - Other professional, scientific and technical activities n.e.c.
Q.86.90 - Other human health activities
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The Institute is a leading scientific institution coordinating physiological research in the Republic of Belarus. The institute successfully carries out fundamental and applied research aimed at developing methods for the prevention and correction of pathological conditions of hypoxic, ischemic and inflammatory genesis, and develops new devices and methods for their therapeutic and prophylactic use. The main scientific activity of the departments is currently focused on studying the mechanisms of the formation of pathological conditions of the body (primarily hypoxic and neurodestructive) and substantiating new technologies for prevention, treatment and rehabilitation. Particular attention is paid to the development of complex methods for the treatment of malignant tumors using metabolic blockade effectors and high-intensity pulsed magnetic fields and methods for controlling the proliferation of tumor cells based on changes in the functional state of neuroreceptors in vitro and in vivo, as well as the development of a method for immunotherapy of patients suffering from pancreatic cancer. , using autologous dendritic cells primed with tumor antigens and elucidating new mechanisms of tumor formation, substantiation of prevention methods. Studies of the molecular mechanisms of proliferation, differentiation and oncogenesis are being carried out; physiological and therapeutic effect of physical factors and the development of new technologies of physiotherapy and physiotherapy equipment and experimental analysis of positive and negative aspects of the use of nanoparticles and heterocyclic compounds in biomedical technologies. The neurophysiological bases of dysregulation of the functions of internal organs during ischemia of the nervous tissue of various origins are being studied. Works on the physiology of nutrition and sports are being carried out. Preclinical studies of drugs and nanomaterials are underway. Research is being carried out on the safety of biosubstances, biotherapeutic agents, pharmacological complexes and medical products on the basis of agreements with manufacturing enterprises and research institutions. The staff of the Institute conducts research on the mechanisms of interaction between neurons and glial cells in normal and pathological conditions. The functional role of biological preparations (platelet-rich plasma, suspension of mitochondria, mesenchymal stem cells, etc.) in the activation of reparative processes in strokes and brain injuries, ischemia of the lower extremities is being studied. Methods for stable remote monitoring of vital human functions (heart, blood vessels, respiration, temperature, motor activity, brain activity) are being developed. Particular attention is paid to the study of the functional role of the extracellular matrix and stem cells in the development of neoplasms. Cell technologies are being developed for the treatment of malignant diseases. The Institute also evaluates the therapeutic and therapeutic-prophylactic properties of natural mineral waters and the effectiveness of pre- and probiotics - food, food supplements.

Close scientific cooperation is carried out with scientists from Russia, China and Uzbekistan.
Languages spoken
English
Russian

Information about partnership

Type of partnership considered
Outsourcing agreement
Subcontracting
Type and role of partner sought
Consumers interested in purchasing services to study the mechanisms of positive and negative effects on the functional status of the body of foods, diets and biologically active food supplements and the functional role of the normal intestinal microflora and its changes depending on the diet or the effects of biologically active substances under an outsourcing agreement or a subcontracting.

Partners interested in the development of services for the study of the mechanisms of positive and negative effects on the functional status of the body of foods, diets and biologically active food supplements and the functional role of the normal intestinal microflora and its changes depending on the diet or the effects of biologically active substances under a research cooperation agreement.
Type and size of partner sought
> 500
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
Sole proprietor
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Statistics since 25.08.2023 01:54:55