Institute of Chemistry of New Materials

http://ichnm.by/  
220141 Minsk, F.Skaryna str., 36

Biopolymer films - carriers of mesenchymal stem cells

COUNTRY OF ORIGIN

IDENTIFIER

TO3366

PUBLISHED

2021-01-16

LAST UPDATE

2021-02-26

DEADLINE

Linked profile in other language
Responsible
Darya Boika
+375 17 265 8843
dashik92_1992@mail.ru
Summary
The Institute of Chemistry of New Materials has developed multilayer coatings for modifying surgical meshes in order to immobilize viable mesenchymal stem cells on them. The key influence on cell adhesion is exerted by the elastic properties of multilayer films. The Institute is looking for partners to organize work within the framework of an agreement on scientific and technical cooperation.
Description
Ultra-thin coatings (thickness <100 nm) based on polysaccharides (chitosan, pectin, dextran, carboxymethylcellulose) ensure effective adhesion (attachment) of mesenchymal stem cells in a viable state. The relationship between the physicochemical characteristics of ultrathin biopolymer films and the ability of mesenchymal stem cells to form on their surface a monolayer culture of fibroblast-like cells with high viability (at least 95% of viable cells) has been established.

The developed multilayer coatings can be used for modification of surgical meshes in order to immobilize viable mesenchymal stem cells on them.
Advantages and Innovations
The relationship between the properties and composition of ultrathin biopolymer multilayer films and the adhesion and functioning of mesenchymal stem cells on them has been established. It has been proven that the key effect on cell adhesion is exerted by the elastic properties of multilayer films.
Stage of development
Prototype available for demonstration (TRL7)
Funding source
State budged
Internal
IPR status
Exclusive rights
Secret know-how
Sector group
BioChemTech
Healthcare
Materials

Organization information

Type
R&D institution
Year established
1998
NACE keywords
C.21.10 - Manufacture of basic pharmaceutical products
M.72.19 - Other research and experimental development on natural sciences and engineering
M.72.11 - Research and experimental development on biotechnology
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The Institute conducts research in broad international scientific cooperation with research centers in Russia, Azerbaijan, China, Vietnam, Saudi Arabia, USA, Poland, Germany, Italy, Israel, Republic of Korea, regularly holds International conferences on the problems of obtaining high-tech low-tonnage chemical products for various functional purposes, as well as alternative sources of raw materials and fuels.
Languages spoken
English
Russian

Information about partnership

Type of partnership considered
Research cooperation agreement
Type and role of partner sought
Partners interested in joint work in the field of biopolymer films.
Type and size of partner sought
SME <= 10
R&D Institution
University
Sole proprietor

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