Institute of Bioorganic Chemistry

http://iboch.bas-net.by/  

Medicinal product - antitumor drug Azacitidine and technology for producing the substance

COUNTRY OF ORIGIN

Belarus

IDENTIFIER

BO4705

PUBLISHED

2022-01-14

LAST UPDATE

2022-01-16

DEADLINE

Linked profile in other language
Responsible
Svetlana Babitskaia
info@iboch.by
Summary
The Institute of Bioorganic Chemistry offers consumers a medicinal product - the antitumor drug Azacitidine on the basis of a manufacturing agreement, a technology for obtaining a substance for the drug on the basis of a license agreement and is looking for partners to conclude a distribution services agreement.
Description
Antitumor drug Azacitidine for treatment
* myelodysplastic syndrome (MDS) with intermediate-2 or high risk on the IPSS scale;
* acute myeloid leukemia (AML);
* chronic myelomonocytic leukemia without signs of MDS.
Advantages and Innovations
The antitumor effect is due to the cytotoxicity of the drug against pathologically altered hematopoietic cells of the bone marrow, its ability to cause DNA hypomethylation.
Stage of development
Field tested/evaluated (TRL8)
Comments regarding stage of development
The technology for the production of the pharmaceutical substance Azacitidine, the dosage form of the drug Azacitidine, regulatory and technical documentation have been developed. Clinical trials of the drug are underway.
Funding source
State budged
Internal
IPR status
Exclusive rights
Secret know-how
Sector group
BioChemTech
Healthcare

Client information

Type
R&D institution
Year established
1974
NACE keywords
C.20.59 - Manufacture of other chemical products n.e.c.
C.21.10 - Manufacture of basic pharmaceutical products
C.21.20 - Manufacture of pharmaceutical preparations
M.72.19 - Other research and experimental development on natural sciences and engineering
M.74.90 - Other professional, scientific and technical activities n.e.c.
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The institute has an experimental base for studying the biological activity of the obtained compounds at the cellular level and in tests on animal models. For pilot production of the developed products (hemosorbents, preparations of recombinant enzymes, immunochemical reagents, oxyphitosterols, etc.), 5 experimental production sites have been created at the institute.

The results of fundamental and applied research on methods and means of protecting plants from diseases, insects, weeds, and other unfavorable environmental factors that are safe for humans and the biosphere as a whole were the basis for the development of methods for obtaining new plant growth stimulators, pheromone compositions (pheromones of the codling moth LP -U and mill moth), active ingredients of pesticides (analogs of the herbicide Grasp and insecticide Confidor), formulations of pesticides (herbicides, insecticides, fungicides, etc.).

The created intellectual property of the Institute today consists of patents maintained in force, laboratory technological and experimental industrial regulations, technical specifications, and trademarks. Licensing agreements are in force for the transfer of technologies for the production of immunodiagnostic products, hemosorbents, and pesticides to manufacturers.
Languages spoken
English
Russian

Information about partnership

Type of partnership considered
Distribution services agreement
License agreement
Manufacturing agreement
Type and role of partner sought
Consumers interested in purchasing the anticancer drug Azacitidine under a manufacturing agreement.

Distributors interested in purchasing the anticancer drug Azacitidine under a distribution services agreement.

Partners interested in acquiring technology for obtaining the substance of the anticancer drug Azacitidine under a license agreement.
Type and size of partner sought
> 500 MNE
> 500
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University

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