The Institute of Biochemistry of Bioactive Compounds offers consumers a hepatoprotective agent containing berberine and silymarin in a self-emulsifying delivery system under a manufacturing agreement, offers services for the development of methods for the use of a hepatoprotective agent under an outsourcing agreement, and is looking for partners interested in a distribution service agreement.

A product based on milk thistle flavonoids and berberine in a self-emulsifying delivery system has been developed; studies indicate a high hepatoprotective, anti-inflammatory and anti-fibrotic activity of the combination of milk thistle flavonoids (silymarin) and berberine as part of the developed self-emulsifying delivery system.

An increase in the bioavailability of berberine and silymarin in the composition of the developed self-emulsifying delivery system was shown compared to their use in a free form; a pronounced hepatoprotective effect of the combination of these flavonoids was found in acute and subchronic liver damage with carbon tetrachloride and acute damage with toxic doses of acetaminophen, superior to the effect of silymarin and berberine and a combination of drugs in free form.

In the structural subdivisions of the institute, research is carried out in the field of vitaminology, the study of molecular mechanisms of regulation of metabolism in normal and pathological conditions, the biochemistry of alcohol and drug addiction, neurochemistry and pharmacology.

The main activities are as follows: conducting fundamental and applied research aimed at studying the mechanisms of pathogenesis of diseases of the liver, cardiovascular and endocrine systems, alcohol dependence, pathological conditions associated with a deficiency of essential micronutrients and the effects of stress, in order to develop methods for their prevention, diagnosis and therapy; development of new innovative medicines, vitamin preparations, dietary supplements, as well as the development of methods for the isolation and purification of biologically active compounds from herbal medicinal raw materials, the development of their laboratory production for the needs of the pharmaceutical industry.

The Institute has developed unique technologies for obtaining dry extracts from medicinal plant materials and spicy-aromatic plants for use as components:
- in the production of dietary supplements,
- in the food industry,
- in the production of perfumery.

Production under the order of products of deep processing and purification of extracts from vegetable raw materials for use as analytical standards is possible.

Consumers interested in purchasing a hepatoprotective product containing berberine and silymarin in a self-emulsifying delivery system under a manufacturing agreement.

Consumers interested in services for the development of methods for the use of a hepatoprotective agent under an outsourcing agreement.

Distributors, interested in purchasing a hepatoprotective product containing berberine and silymarin in a self-emulsifying delivery system under a distribution service agreement.