State scientific and production association «Chemical Synthesis and Biotechnology» of the National Academy of Sciences of Belarus offers consumers probiotic preparation «BACTO-HEALTH» for prevention and treatment of bacterial diseases infecting valuable fish species under a manufacturing agreement and is looking for partners interested in a distribution services agreement.

State scientific and production association «Chemical Synthesis and Biotechnology» of the National Academy of Sciences of Belarus manufactures probiotic preparation «BACTO-HEALTH», designed for prevention and treatment of bacterial diseases infecting sturgeon and salmon fish.

The based of the preparation consists of cells, spores, metabolic products of bacteria Bacillus amyloliquefaciens (titer - not less than 1.0×10⁹ CFU/g).

The Bacillus amyloliquefaciens strain, which forms the bulk of preparation, is characterized by:
* high antagonistic activity against bacteria that cause sturgeon and salmon fish;
* positive effect on the natural (nonspecific) resistance of the fish organism;
* ability to stimulate fish digestion due to enzymatic activity.

Probiotic preparation «BACTO-HEALTH» is harmless to warm-blooded animals and fish, allows you to get environmentally friendly products.

Efficiency:
* increases the bactericidal activity of blood serum of sturgeon and salmon fish – by 32.2% and 69.4%;
* phagocytic activity of leukocytes – by 30.9% and 48.9%;
* phagocytic index – by 109% and 83.8%;
* phagocytic number – 1.7 times.

Application guidelines for valuable fish species:

Dosage	Treatment	Number of treatments
400 g of probiotic / 1 t of compound feed	Admixed to rations and fed perorally once a day during 5 days (diurnal dose – 3% of fish weight)	One may suffice. If necessary, therapy course is repeated in 7..10 days depending on epizootic situation
10 g of probiotic / 1 m3 of water	Therapeutic baths taken once a day with 20 min cessation of water flow during 5 day period

Package:
Plastic or metallized bags of 1 kg, 5 kg, 10 kg weight.

Terms of storage:
12 months since fabrication within temperature range 0 to +15 °С in shady place.

Application area: fish farming.

SSPA «Chemical Synthesis and Biotechnology» offers partners:
* probiotic preparation «BACTO-HEALTH» for prevention and treatment of bacterial diseases infecting valuable fish species under a manufacturing agreement;
* probiotic preparation «BACTO-HEALTH» for prevention and treatment of bacterial diseases infecting valuable fish species under a distribution services agreement.

Product catalog of the SSPA «Chemical Synthesis and Biotechnology» 2023, p.29.

Link on the SSPA «Chemical Synthesis and Biotechnology» site (in Russian).

Import substitution of probiotic preparations:
«Amilocin» («Arlen» LLC, Russian Federation);
«Provagen» («Stovek» LLC, Russian Federation);
«Aquapurin» («Research Center» SPC LLC, Russian Federation);
«Subtilis» («Research Institute of Probiotics» LLC, Russian Federation).

ТУ BY 100289066.156-2019
Registration certificate № 6590-10-19 BPPI

SSPA «Chemical Synthesis and Biotechnology» carries out the following activities:
* monitoring the state of the biotechnological sector of the economy;
* biologization of photoprotective measures based on the development and implementation of microbial preparations that ensure effective control of plant diseases of bacterial and fungal etiology;
* study of the microbiome of soil, plants, animals and humans as a source of genetic resources for the development of innovative biotechnologies;
* development and implementation of veterinary probiotic drugs and feed additives for animal husbandry, poultry farming, pond fish farming;
* creation of environmentally friendly detergents with a disinfecting effect, enriched with probiotic bacteria;
* molecular diagnostics and regulation of the composition of microbiocenoses of man-made ecosystems;
* molecular diagnostics of micromycetes that cause mold damage to construction sites, in order to develop highly effective means of protection against biological damage.

Consumers interested in purchasing probiotic preparation «BACTO-HEALTH» for prevention and treatment of bacterial diseases infecting valuable fish species under a manufacturing agreement.

Partners interested in purchasing probiotic preparation «BACTO-HEALTH» for prevention and treatment of bacterial diseases infecting valuable fish species under a distribution services agreement.