Manufacture and supply of biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures
COUNTRY OF ORIGIN
BelarusIDENTIFIER
BO10816PUBLISHED
2026-11-10LAST UPDATE
2026-11-10DEADLINE
Linked profile in other language
Responsible
Tatiana Petkevich
+375 44 750 7890
inmisale@mail.ru
+375 44 750 7890
inmisale@mail.ru
Summary
The Institute of Microbiology of the National Academy of Sciences of Belarus offers consumers biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a manufacturing agreement and is looking for partners interested in a distribution services agreement.
Description
The Institute of Microbiology of the National Academy of Sciences of Belarus together with the EE «Belarusian State Technological University» has developed biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures.
The based of preparation is oidiospores and mycelium fragments of basidiomycete Phlebiopsis gigantea;
(titer – not less than 3,5x106 CFU/ml).
Principle of action:
Phlebiopsis gigantea (giant phlebiopsis) is a local saprotrophic basidiomycete, responsible for degradation of dead softwood. It is widely used for biological control of variegated sieve rot of roots caused by the fungus Heterobasidion annosum (root sponge).
Biopreparation diminishes the area of root rot infection in pine-trees and curbs its spread in conifers by preventing the access of pathogen to available nutrient substrate – wood of stumps and roots.
Biopreparation is not phytotoxic and not hazardous to humans, animals, fowl, fish, beneficial insects.
Application guidelines:
Package:
Plastic containers of 1 l volume.
Terms of storage:
6 months since fabrication date within temperature range +4 to +6 °C in shady place.
Application area: forestry.
Institute of Microbiology offers partners:
* biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a manufacturing agreement;
* biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a distribution services agreement.
Product catalog of the «Institute of Microbiology of NAS of Belarus» 2023, p.6.
Link on the Institute of Microbiology site (in Russian).
The based of preparation is oidiospores and mycelium fragments of basidiomycete Phlebiopsis gigantea;
(titer – not less than 3,5x106 CFU/ml).
Principle of action:
Phlebiopsis gigantea (giant phlebiopsis) is a local saprotrophic basidiomycete, responsible for degradation of dead softwood. It is widely used for biological control of variegated sieve rot of roots caused by the fungus Heterobasidion annosum (root sponge).
Biopreparation diminishes the area of root rot infection in pine-trees and curbs its spread in conifers by preventing the access of pathogen to available nutrient substrate – wood of stumps and roots.
Biopreparation is not phytotoxic and not hazardous to humans, animals, fowl, fish, beneficial insects.
Application guidelines:
plantations | rots | 10 l of water / 15 m2 of stump surface | Pine cutting is followed by stump treatment immediately or within 1 week thereafter. The biocontrol agent is applied with sprayer or brush to attain uniform coloring of stumps |
Package:
Plastic containers of 1 l volume.
Terms of storage:
6 months since fabrication date within temperature range +4 to +6 °C in shady place.
Application area: forestry.
Institute of Microbiology offers partners:
* biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a manufacturing agreement;
* biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a distribution services agreement.
Product catalog of the «Institute of Microbiology of NAS of Belarus» 2023, p.6.
Link on the Institute of Microbiology site (in Russian).
Advantages and Innovations
Import substitution of biopreparations:
«Rotstop» («Verdera Oy», Finland);
«PG suspension» («Forest Research», Great Britain).
«Rotstop» («Verdera Oy», Finland);
«PG suspension» («Forest Research», Great Britain).
Stage of development
Already on the market
Comments regarding stage of development
ТУ BY 100289066.146-2018
Registration certificate № 11-06-0109
Registration certificate № 11-06-0109
Funding source
State budged
Internal
Internal
IPR status
Exclusive rights
Secret know-how
Trade marks
Secret know-how
Trade marks
Sector group
Agrofood
BioChemTech
Environment
Materials
BioChemTech
Environment
Materials
Client information
Type
R&D institution
Year established
1975
NACE keywords
C.20.20 - Manufacture of pesticides and other agrochemical products
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
A.02.10 - Silviculture and other forestry activities
M.74.90 - Other professional, scientific and technical activities n.e.c.
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
A.02.10 - Silviculture and other forestry activities
M.74.90 - Other professional, scientific and technical activities n.e.c.
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The Institute of Microbiology is the leading research center of the Republic of Belarus in the field of microbiology and biotechnology. The Institute's arsenal of innovative developments includes substances for medicines and diagnostics, biopreservatives, feed and food additives, biodisinfectants, probiotics, plant protection products, microbial fertilizers, wastewater and environmental treatment technologies that are in demand by the economy, and specific recommendations for combating biodamage.
Main areas of scientific activity:
— Study of the biodiversity, ecology, physiology, biochemistry, and genetics of microorganisms; development of a national repository of microbial biological resources.
— Selection and genetic engineering of microbial strains capable of producing biologically active compounds of practical significance.
— Development of microbial biotechnologies for industry, agriculture, medicine, and environmental protection.
Key objectives:
— Ensuring the preservation and operation of the Belarusian Collection of Non-Pathogenic Microorganisms (designated as a National Heritage Asset, No. 5), which is registered with the World Federation for Culture Collections (acronym: BIM; collection number: 909). Expanding the collection and the DNA bank of industrially valuable microorganisms.
— Phenotypic and molecular-genetic identification of microorganisms; selection and genetic engineering of strains that produce biologically active compounds.
— Elucidating the mechanisms underlying the biogenesis of enzymes and low-molecular-weight metabolites. Developing production technologies and pilot-scale manufacturing of enzyme preparations for the chemo-enzymatic synthesis of pharmaceutical substances, the production of diagnostic agents, and applications in the food industry and waste processing.
— Developing and implementing technologies for the production of microbial preparations for agriculture and forestry, including biological plant protection agents, microbial fertilizers, bio-preservatives, feed additives, and probiotics.
— Creating environmental biotechnologies and preparations for the remediation of natural and industrial environments contaminated with xenobiotics or petroleum-based pollutants.
— Establishing biotechnological platforms for the production of vaccines. — Development of biotechnologies for the microbial conversion of plant-based raw materials and the production of high-quality animal feed.
— Pilot-scale industrial production of environmentally safe biological preparations for various applications.
— Scientific support for biotechnological manufacturing processes.
Official website of the Institute of Microbiology.
Main areas of scientific activity:
— Study of the biodiversity, ecology, physiology, biochemistry, and genetics of microorganisms; development of a national repository of microbial biological resources.
— Selection and genetic engineering of microbial strains capable of producing biologically active compounds of practical significance.
— Development of microbial biotechnologies for industry, agriculture, medicine, and environmental protection.
Key objectives:
— Ensuring the preservation and operation of the Belarusian Collection of Non-Pathogenic Microorganisms (designated as a National Heritage Asset, No. 5), which is registered with the World Federation for Culture Collections (acronym: BIM; collection number: 909). Expanding the collection and the DNA bank of industrially valuable microorganisms.
— Phenotypic and molecular-genetic identification of microorganisms; selection and genetic engineering of strains that produce biologically active compounds.
— Elucidating the mechanisms underlying the biogenesis of enzymes and low-molecular-weight metabolites. Developing production technologies and pilot-scale manufacturing of enzyme preparations for the chemo-enzymatic synthesis of pharmaceutical substances, the production of diagnostic agents, and applications in the food industry and waste processing.
— Developing and implementing technologies for the production of microbial preparations for agriculture and forestry, including biological plant protection agents, microbial fertilizers, bio-preservatives, feed additives, and probiotics.
— Creating environmental biotechnologies and preparations for the remediation of natural and industrial environments contaminated with xenobiotics or petroleum-based pollutants.
— Establishing biotechnological platforms for the production of vaccines. — Development of biotechnologies for the microbial conversion of plant-based raw materials and the production of high-quality animal feed.
— Pilot-scale industrial production of environmentally safe biological preparations for various applications.
— Scientific support for biotechnological manufacturing processes.
Official website of the Institute of Microbiology.
Languages spoken
English
Russian
Russian
Information about partnership
Type of partnership considered
Distribution services agreement
Manufacturing agreement
Manufacturing agreement
Type and role of partner sought
Consumers interested in purchasing biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a manufacturing agreement.
Partners interested in purchasing biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a distribution services agreement.
Partners interested in purchasing biopreparation «PHLEBIOPIN» for limiting deleterious effect of root rot infection in pine plantations during improvement cuts and other sanitation measures under a distribution services agreement.
Type and size of partner sought
> 500
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
Sole proprietor
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
Sole proprietor
Attachments
Biopreparation «PHLEBIOPIN».JPG

Antagonistic activity of suspension of oidium (1) and mycelium (pellets) (1a) of Phlebiopsis gigantea against root rot pathogen Heterobasidion annosum (2).jpeg
 and mycelium (pellets) (1a) of Phlebiopsis gigantea against root rot pathogen Heterobasidion annosum (2).jpeg)
Wood affected by root sponge.jpeg

Limitation of harmful effect of the root sponge in pine plantations during felling.jpeg

Antagonistic activity of suspension of oidium (1) and mycelium (pellets) (1a) of Phlebiopsis gigantea against root rot pathogen Heterobasidion annosum (2).jpeg
 and mycelium (pellets) (1a) of Phlebiopsis gigantea against root rot pathogen Heterobasidion annosum (2).jpeg)
Wood affected by root sponge.jpeg

Limitation of harmful effect of the root sponge in pine plantations during felling.jpeg

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Statistics since 10.11.2026 11:28:17
Statistics since 10.11.2026 11:28:17
