State scientific and production association «Chemical Synthesis and Biotechnology» of the National Academy of Sciences of Belarus offers consumers probiotic preparation «EMILIN» for prevention and treatment of bacterial diseases in carp fish species under a manufacturing agreement and is looking for partners interested in a distribution services agreement.

State scientific and production association «Chemical Synthesis and Biotechnology» of the National Academy of Sciences of Belarus manufactures probiotic preparation «EMILIN», designed for prevention and treatment of bacterial diseases in carp fish species.

The based of the preparation consists of cells, spores and metabolic products of 2 strains of spore-forming bacteria Bacillus subtilis (titer - not less than 1.0×10⁹ CFU/g).

Bacillus subtilis strains, which form the base of the preparacion, are characterized by high antagonistic activity against pathogenic and opportunistic bacteria - pathogens of fish diseases, including representatives of the genera Aeromonas, Pseudomonas, Sphingobacterium, Flavobacterium, Vibrio, etc.

The preparation «EMILIN» is harmless to humans, animals, birds, fish, and beneficial insects. Its use makes it possible to obtain environmentally friendly products.

Efficiency:
* reduces the level of contamination of the internal organs of fish with pathogenic, opportunistic microbiota from 80..100% to trace amounts;
* increases the natural (non-specific) resistance of the carp body:
• bactericidal activity of blood serum – by 17.7%;
• phagocytic activity of leukocytes – by 17.0%;
• phagocytic index – by 1.8%;
• phagocytic number – 2 times;
* increases the resilience of fish and the ability to tolerate stress during the wintering period:
• the output of fish from wintering is 97%;
• fish weight increases by 10%.

Application guidelines for carp fish species:

Dosage	Treatment	Number of treatments
200 g of probiotic / 1 t of compound feed	Admixed to rations and fed perorally once a day during 5 days (diurnal dose – 5% of fish weight)	One cycle of therapy may be sufficient. If necessary, repeat the course in 7..10 days depending on epizootic situation
10 g of probiotic / 1 m3 of water reservoir	Therapy baths are practiced once a day with 20 min intermission of water exchange during 5 day period

Package:
Plastic or metallized bags of 0,5 kg to 25 kg weight.

Terms of storage:
12 months since fabrication within temperature range 0 to +15°С in shady place.

Application area: fish farming.

SSPA «Chemical Synthesis and Biotechnology» offers partners:
* probiotic preparation «EMILIN» for prevention and treatment of bacterial diseases in carp fish species under a manufacturing agreement;
* probiotic preparation «EMILIN» for prevention and treatment of bacterial diseases in carp fish species under a distribution services agreement.

Product catalog of the SSPA «Chemical Synthesis and Biotechnology» 2023, p.30.

Link on the SSPA «Chemical Synthesis and Biotechnology» site (in Russian).

Import substitution of probiotic preparations:
«SUB-PRO» («VectorEuro» LCC, Russian Federation);
«Probiotic for fattening fish» («Biohelper», Russian Federation);
«Koi Junior All Seasons Probiotic» («Sera», Germany);
«Bioclean Aqua Fish Probiotics» («Organica Biotech Private Limited», India).

ТУ BY 100289066.133-2015
Registration certificate № 7899-10-21 BPPI

SSPA «Chemical Synthesis and Biotechnology» carries out the following activities:
* monitoring the state of the biotechnological sector of the economy;
* biologization of photoprotective measures based on the development and implementation of microbial preparations that ensure effective control of plant diseases of bacterial and fungal etiology;
* study of the microbiome of soil, plants, animals and humans as a source of genetic resources for the development of innovative biotechnologies;
* development and implementation of veterinary probiotic drugs and feed additives for animal husbandry, poultry farming, pond fish farming;
* creation of environmentally friendly detergents with a disinfecting effect, enriched with probiotic bacteria;
* molecular diagnostics and regulation of the composition of microbiocenoses of man-made ecosystems;
* molecular diagnostics of micromycetes that cause mold damage to construction sites, in order to develop highly effective means of protection against biological damage.

Consumers interested in purchasing probiotic preparation «EMILIN» for prevention and treatment of bacterial diseases in carp fish species under a manufacturing agreement.

Partners interested in purchasing probiotic preparation «EMILIN» for prevention and treatment of bacterial diseases in carp fish species under a distribution services agreement.