Institute of Physiology

http://physiology.by/  
220072 Minsk, Academic St., 28

Biological modeling

COUNTRY OF ORIGIN

Belarus

IDENTIFIER

BO7474

PUBLISHED

2023-08-24

LAST UPDATE

2023-08-29

DEADLINE

Linked profile in other language
Responsible
Tatiana Khrustaleva
+375 17 378 1630
biblio@fizio.bas-net.by
Summary
The Institute offers consumers services in the field of biological modeling-the study of the biological action of lipid signaling molecules, the study of the mechanisms of the influence of physical factors on physiological processes in the body in normal and pathological conditions, the study of the protective potential of mesenchymal stem cells of adipose tissue under an outsourcing agreement or a subcontracting and is loocking for partners interested in a research cooperation agreement.
Description
In the field of biological modeling, services are offered for:
- study of the biological action of signal lipid molecules with cannabimimetic properties;
studying the mechanisms of the influence of physical factors on physiological processes in the body in normal and pathological conditions;
study of the protective potential of mesenchymal stem cells of adipose tissue in modeling various pathological processes and conditions.

The laboratory of the institute is equipped with equipment for:
- electrophysiological studies;
- determination of the parameters of the main exchange;
- thermometry;
- psychophysiological studies;
- non-invasive measurement of blood pressure in rodents;
- registration of the electrocardiogram of rats;
- hematological examination of the blood of experimental animals;
- studies of gait patterns in laboratory animals using the hardware and software complex "Cat Walk", the Netherlands;
- studies of nociceptive reactions in experimental animals, etc.
Advantages and Innovations
Unique research methods. Highly qualified staff.
Stage of development
Already on the market
Funding source
State budged
Internal
IPR status
Exclusive rights
Secret know-how
Sector group
BioChemTech
Healthcare

Client information

Type
R&D institution
Year established
1953
NACE keywords
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
M.74.90 - Other professional, scientific and technical activities n.e.c.
Q.86.90 - Other human health activities
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The Institute is a leading scientific institution coordinating physiological research in the Republic of Belarus. The institute successfully carries out fundamental and applied research aimed at developing methods for the prevention and correction of pathological conditions of hypoxic, ischemic and inflammatory genesis, and develops new devices and methods for their therapeutic and prophylactic use. The main scientific activity of the departments is currently focused on studying the mechanisms of the formation of pathological conditions of the body (primarily hypoxic and neurodestructive) and substantiating new technologies for prevention, treatment and rehabilitation. Particular attention is paid to the development of complex methods for the treatment of malignant tumors using metabolic blockade effectors and high-intensity pulsed magnetic fields and methods for controlling the proliferation of tumor cells based on changes in the functional state of neuroreceptors in vitro and in vivo, as well as the development of a method for immunotherapy of patients suffering from pancreatic cancer. , using autologous dendritic cells primed with tumor antigens and elucidating new mechanisms of tumor formation, substantiation of prevention methods. Studies of the molecular mechanisms of proliferation, differentiation and oncogenesis are being carried out; physiological and therapeutic effect of physical factors and the development of new technologies of physiotherapy and physiotherapy equipment and experimental analysis of positive and negative aspects of the use of nanoparticles and heterocyclic compounds in biomedical technologies. The neurophysiological bases of dysregulation of the functions of internal organs during ischemia of the nervous tissue of various origins are being studied. Works on the physiology of nutrition and sports are being carried out. Preclinical studies of drugs and nanomaterials are underway. Research is being carried out on the safety of biosubstances, biotherapeutic agents, pharmacological complexes and medical products on the basis of agreements with manufacturing enterprises and research institutions. The staff of the Institute conducts research on the mechanisms of interaction between neurons and glial cells in normal and pathological conditions. The functional role of biological preparations (platelet-rich plasma, suspension of mitochondria, mesenchymal stem cells, etc.) in the activation of reparative processes in strokes and brain injuries, ischemia of the lower extremities is being studied. Methods for stable remote monitoring of vital human functions (heart, blood vessels, respiration, temperature, motor activity, brain activity) are being developed. Particular attention is paid to the study of the functional role of the extracellular matrix and stem cells in the development of neoplasms. Cell technologies are being developed for the treatment of malignant diseases. The Institute also evaluates the therapeutic and therapeutic-prophylactic properties of natural mineral waters and the effectiveness of pre- and probiotics - food, food supplements.

Close scientific cooperation is carried out with scientists from Russia, China and Uzbekistan.
Languages spoken
English
Russian

Information about partnership

Type of partnership considered
Outsourcing agreement
Subcontracting
Type and role of partner sought
Consumers interested in purchasing services in the field of biological modeling - the study of the biological action of signal lipid molecules, the study of the mechanisms of influence of physical factors on physiological processes in the body in normal and pathological conditions, the study of the protective potential of mesenchymal stem cells of adipose tissue under an outsourcing agreement or a subcontracting.

Partners interested in the development of biological modeling - studies of the biological action of signal lipid molecules, study of the mechanisms of the influence of physical factors on physiological processes in the body in normal and pathological conditions, study of the protective potential of mesenchymal stem cells of adipose tissue under a research cooperation agreement.
Type and size of partner sought
> 500
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
Views: 85
Statistics since 24.08.2023 15:05:47